Phenylmethyl 4-[[[(1,1-dimethylethyl)oxy]carbonyl]amino]-1-piperidinecarboxylate - Names and Identifiers
Phenylmethyl 4-[[[(1,1-dimethylethyl)oxy]carbonyl]amino]-1-piperidinecarboxylate - Physico-chemical Properties
Molecular Formula | C18H26N2O4
|
Molar Mass | 334.41 |
Density | 1.15±0.1 g/cm3(Predicted) |
Boling Point | 471.9±44.0 °C(Predicted) |
pKa | 12.30±0.20(Predicted) |
Storage Condition | 2-8°C |
Phenylmethyl 4-[[[(1,1-dimethylethyl)oxy]carbonyl]amino]-1-piperidinecarboxylate - Risk and Safety
Safety Description | 24/25 - Avoid contact with skin and eyes.
|
HS Code | 29333990 |
Phenylmethyl 4-[[[(1,1-dimethylethyl)oxy]carbonyl]amino]-1-piperidinecarboxylate - Introduction
1-CBZ-4-(BOC-AMINO)PIPERIDINE is an organic compound derived from the reaction of 1-aminopiperidine with P-benzoyl chloride and butanolic acid (Boc).
1-CBZ-4-(BOC-AMINO)PIPERIDINE has the following properties:
-Appearance: Colorless to slightly yellow solid
-Molecular formula: C17H24N2O2
-Molecular weight: 288.39g/mol
-Melting point: 75-80 ° C
-Solubility: Soluble in organic solvents such as dimethyl sulfoxide (DMSO) and methanol
1-CBZ-4-(BOC-AMINO)PIPERIDINE is commonly used as a protecting group in organic synthesis to protect the nitrogen atom of an amino compound from interference by other reactants. It has a wide range of applications in the field of drug synthesis, catalytic reaction and polymerization. Its Main uses include:
-As an amino protective agent: 1-CBZ-4-(BOC-AMINO)PIPERIDINE can protect amino compounds so that they do not react under certain reaction conditions to prevent side reactions.
-drug synthesis: in the synthesis of drugs, 1-CBZ-4-(BOC-AMINO)PIPERIDINE can be through the protection of amino compounds to achieve selective reaction, improve the synthesis efficiency.
-Catalytic reaction: 1-CBZ-4-(BOC-AMINO)PIPERIDINE can play the role of a ligand in some catalytic reactions and promote the progress of the reaction.
There are some safety precautions to note when using 1-CBZ-4-(BOC-AMINO)PIPERIDINE, including:
-Since 1-CBZ-4-(BOC-AMINO)PIPERIDINE is an organic compound, it should be operated in a well-ventilated laboratory environment to avoid inhalation or contact with skin and eyes.
-For inhalation or exposure, rinse immediately with water and seek professional medical help.
-When storing, keep 1-CBZ-4-(BOC-AMINO)PIPERIDINE in a dry, cool place, away from fire and oxidizing agents.
-Avoid contact with strong oxidants, strong acids and other substances to avoid dangerous reactions.
Last Update:2024-04-09 21:04:16